合同定制-宁波美诺华药业股份有限公司

Rosuvastatin
瑞舒伐他汀钙

Rosuvastatin methyl ester

147118-40-9

ZL200910053047.3
ZL201511022824.X
ZL201511022872.9
ZL201511023253.1
ZL201510940531.3

Rosuvastatin tert-butyl ester

355806-00-7

Tert-butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate

289042-12-2

Atorvastatin
阿托伐他汀钙

4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β- diphenylbenzene butaneamide

125971-96-2

ZL200810202127.6

Diprotected Atorvastatin (L1)

125971-95-1

Perindopril
培哚普利

N-[(S)-1-Carbethoxybutyl]-(S)-alanine

82834-12-6

ZL201210555176.4
ZL200910266685.3

(S)-Indoline-2-carboxylic acid

79815-20-6

(2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid

80875-98-5

(2S,3aS,7aS)-Benzyl octahydro-1H-indole-2-carboxylate 4-methylbenzenesulfonate

94062-52-9

Ivabradine
伊伐布雷定

3-(3-Iodopropyl)-7,8-dimethoxy-1,3-dihydro-2H-3-benzapine-2-one

148870-57-9

ZL201010207206.3
ZL201510099954.7
ZL201511018565.3

[N-[[3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl] carbonyl]-N-methylamine]

866783-13-3

7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one

73942-87-7

Candesartan
坎地沙坦

Trityl candesartan

139481-72-4

ZL201010229921.7
ZL201510671739.X

Ezetimibe
依替米贝

(4s)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone

189028-93-1

ZL201511030652.0

(S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one

189028-95-3

Methyl 3-[(2S,3R)-2-[4-(benzyloxy)phenyl]-1-(4-fluorophenyl)-4-oxoazetidin-3-yl]propanoate

204589-80-0

1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-[4-(phenylmethoxy)phenyl]-(3R,4S)-2-azetidinone

190595-65-4

Galantamine
加兰他敏

(+/-) Nawedine

1668-86-6

4a,5,9,10,11,12-Hexahydro-1-bromo-3-methoxy-11-formyl- 6H-Benzofuro[3a,3,2-ef][2] benzazepine-6-one

122584-14-9

Valsartan
缬沙坦

Methyl N-[(2’-Cyanobiphenyl-4-yl)methyl]-L-valinate hydrochloride

482577-59-3

ZL201010173862.6
ZL201510945518.7

Clopidogrel
氯吡格雷

(S)-Methyl (2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride

141109-19-5

ZL201310462551.5

Pregabalin
普瑞巴林

(R)-(-)-3-(Carbamoylmethyl-5-methylmexanoic acid

181289-33-8

ZL201410137925.0
ZL201410675675.6

3-Carbamoymethyl-5-methylhexanoic acid

181289-15-6

Venlafaxine
文拉法辛

1-[2-Amino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol

130198-05-9

ZL200910100326.0

Duloxetine
度洛西汀

(S)-3-(Methylamino)-1-(2-thienyl)-1-propanol

116539-55-0

ZL201410436429.5

S-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine

132335-44-5

S-(+)-N,N-Dimethyl-3-(1-naphthoxy)-3-(2-thienyl)-1-propylamine oxalate

132335-47-8

Levocetirizine
左西替利嗪

(-)-1-[(4-Chlorophenyl) phenylmethyl]piperazine

300543-56-0

Donepezil
多奈哌齐

5,6-Dimethoxy-2-(4-piperidinylmet hyl)-1-indanone

120014-30-4

Dabigatran
达比加群

Ethyl 3-(4-(methylamino)-3-nitro-N-(pyridin-2-yl)benzamido)propanoate

429659-01-8

ZL201510411877.4

3-[(3-Amino-4-methylaminobenzoyl)pyridin-2-ylamino]propionic acid ethyl ester

212322-56-0

2-(4-Cyanophenylamino)acetic acid

42288-26-6

Ethyl 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino] propionate

211915-84-3

N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanine ethyl ester

429658-95-7

Ropinirole
罗匹尼罗

4-(2-Hydroxyethyl)-2H-indolin-2-one

139122-19-3

Vildagliptin
维格列汀

(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxamide

214398-99-9

ZL201410112710.3

(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile

207557-35-5

Dapagliflozin
达格列净

5-Bromo-2-chloro-4’-ethoxydiphenylmethane

461432-23-5

ZL201510404207.X

Lesinurad
利拉利德

1-Cyclopropyl-4-isothiocyanatonaphthalene

878671-95-5

3H-1,2,4-Triazole-3-thione, 5-amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro

878671-96-6

Isopropyl 2-((5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetate

NA

Sitagliptin
西他列汀

5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione

767340-03-4

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine

486460-32-6

(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one

486460-32-6

Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid

486460-00-8

Safinamide
沙芬酰胺

4-((3-Fluorobenzyl)oxy)benzaldehyde

66742-57-2

ZL201510952335.8

(S)-2((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide

133865-89-1

API	Product Name 产品名称	CAS No.	Structure 结构式	Patent 专利号
Rosuvastatin 瑞舒伐他汀钙	Rosuvastatin methyl ester	147118-40-9		ZL200910053047.3 ZL201511022824.X ZL201511022872.9 ZL201511023253.1 ZL201510940531.3
	Rosuvastatin tert-butyl ester	355806-00-7
	Tert-butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate	289042-12-2
Atorvastatin 阿托伐他汀钙	4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β- diphenylbenzene butaneamide	125971-96-2		ZL200810202127.6
Atorvastatin 阿托伐他汀钙	Diprotected Atorvastatin (L1)	125971-95-1		ZL200810202127.6
Perindopril 培哚普利	N-[(S)-1-Carbethoxybutyl]-(S)-alanine	82834-12-6		ZL201210555176.4 ZL200910266685.3
	(S)-Indoline-2-carboxylic acid	79815-20-6
	(2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid	80875-98-5
	(2S,3aS,7aS)-Benzyl octahydro-1H-indole-2-carboxylate 4-methylbenzenesulfonate	94062-52-9
Ivabradine 伊伐布雷定	3-(3-Iodopropyl)-7,8-dimethoxy-1,3-dihydro-2H-3-benzapine-2-one	148870-57-9		ZL201010207206.3 ZL201510099954.7 ZL201511018565.3
	[N-[[3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl] carbonyl]-N-methylamine]	866783-13-3
	7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one	73942-87-7
Candesartan 坎地沙坦	Trityl candesartan	139481-72-4		ZL201010229921.7 ZL201510671739.X
Ezetimibe 依替米贝	(4s)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone	189028-93-1		ZL201511030652.0
	(S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one	189028-95-3
	Methyl 3-[(2S,3R)-2-[4-(benzyloxy)phenyl]-1-(4-fluorophenyl)-4-oxoazetidin-3-yl]propanoate	204589-80-0
	1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-[4-(phenylmethoxy)phenyl]-(3R,4S)-2-azetidinone	190595-65-4
Galantamine 加兰他敏	(+/-) Nawedine	1668-86-6
Galantamine 加兰他敏	4a,5,9,10,11,12-Hexahydro-1-bromo-3-methoxy-11-formyl- 6H-Benzofuro[3a,3,2-ef][2] benzazepine-6-one	122584-14-9
Valsartan 缬沙坦	Methyl N-[(2’-Cyanobiphenyl-4-yl)methyl]-L-valinate hydrochloride	482577-59-3		ZL201010173862.6 ZL201510945518.7
Clopidogrel 氯吡格雷	(S)-Methyl (2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride	141109-19-5		ZL201310462551.5
Pregabalin 普瑞巴林	(R)-(-)-3-(Carbamoylmethyl-5-methylmexanoic acid	181289-33-8		ZL201410137925.0 ZL201410675675.6
Pregabalin 普瑞巴林	3-Carbamoymethyl-5-methylhexanoic acid	181289-15-6		ZL201410137925.0 ZL201410675675.6
Venlafaxine 文拉法辛	1-[2-Amino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol	130198-05-9		ZL200910100326.0
Duloxetine 度洛西汀	(S)-3-(Methylamino)-1-(2-thienyl)-1-propanol	116539-55-0		ZL201410436429.5
	S-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine	132335-44-5
	S-(+)-N,N-Dimethyl-3-(1-naphthoxy)-3-(2-thienyl)-1-propylamine oxalate	132335-47-8
Levocetirizine 左西替利嗪	(-)-1-[(4-Chlorophenyl) phenylmethyl]piperazine	300543-56-0
Donepezil 多奈哌齐	5,6-Dimethoxy-2-(4-piperidinylmet hyl)-1-indanone	120014-30-4
Dabigatran 达比加群	Ethyl 3-(4-(methylamino)-3-nitro-N-(pyridin-2-yl)benzamido)propanoate	429659-01-8		ZL201510411877.4
	3-[(3-Amino-4-methylaminobenzoyl)pyridin-2-ylamino]propionic acid ethyl ester	212322-56-0
	2-(4-Cyanophenylamino)acetic acid	42288-26-6
	Ethyl 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino] propionate	211915-84-3
	N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanine ethyl ester	429658-95-7
Ropinirole 罗匹尼罗	4-(2-Hydroxyethyl)-2H-indolin-2-one	139122-19-3
Vildagliptin 维格列汀	(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxamide	214398-99-9		ZL201410112710.3
Vildagliptin 维格列汀	(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile	207557-35-5		ZL201410112710.3
Dapagliflozin 达格列净	5-Bromo-2-chloro-4’-ethoxydiphenylmethane	461432-23-5		ZL201510404207.X
Lesinurad 利拉利德	1-Cyclopropyl-4-isothiocyanatonaphthalene	878671-95-5
	3H-1,2,4-Triazole-3-thione, 5-amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro	878671-96-6
	Isopropyl 2-((5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetate	NA
Sitagliptin 西他列汀	5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione	767340-03-4
	(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine	486460-32-6
	(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one	486460-32-6
	Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid	486460-00-8
Safinamide 沙芬酰胺	4-((3-Fluorobenzyl)oxy)benzaldehyde	66742-57-2		ZL201510952335.8
Safinamide 沙芬酰胺	(S)-2((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide	133865-89-1		ZL201510952335.8

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